Systems Biology

The research focus of the Systems Biology DTC is in developing a systems approach to "bridging the gap" between theoretical and experimental knowledge from the level of the individual protein to the level of the whole cell/organism.




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Systems Approaches to Biomedical Science

The EPSRC and MRC SABS-CDT aims to create the next generation of research leaders in drug discovery particularly in the areas of computational and structural therapy discovery, data-driven drug discovery and physiological modelling.




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Synthetic Biology

The EPSRC & BBSRC Synthetic Biology Centre for Doctoral Training (SynBioCDT) provides a 4-year doctoral programme that offers training in the new field of Synthetic Biology, the "Engineering of Biology". This centre is a collaboration between the Universities of Oxford, Bristol and Warwick.

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Interdisciplinary Bioscience DTP

The Interdisciplinary Bioscience Doctoral Training Partnership aims to equip a new generation of bioscience researchers with the skills and knowledge needed to tackle the most important challenges in bioscience research.



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Synthesis for Biology & Medicine

The SBM CDT aims to train next-generation doctoral scientists in the practice of chemical synthesis coupled with an in-depth appreciation of its application to biology and medicine.





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Biomedical Imaging

The Oxford-Nottingham Biomedical Imaging (ONBI) Centre for Doctoral Training, co-sponsored by EPSRC and MRC, aims to train the next generation leaders in the science of biomedical imaging, and offers a uniquely broad training in all imaging methods and scales.



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The centres above are housed in the Rex Richards building at the University of Oxford. You can compare these programmes by pressing the button below.

 
Organisations University of Oxford University of Oxford University of Oxford, Oxford Brookes University, The Pirbright Institute, Diamond Light Source, ISIS, STFC Central Laser Facility, The Research Complex at Harwell University of Oxford University of Oxford, University of Warwick, University of Bristol University of Oxford, University of Nottingham
Research Councils
Academic Background For graduates from physical and life sciences who wish to conduct research in the field of systems biology For graduates from physical and life sciences who wish to undertake research careers at the industrial interface For graduates from life and physical sciences who wish to undertake research in fundamental and applied bioscience For graduates from chemistry who wish to undertake synthetic chemistry research For graduates from engineering, physical, life and medical sciences who wish to conduct research in the field of Synthetic Biology For graduates from primarily a mathematical or physical sciences backgrounds who wish to conduct imaging research in the clinical and life sciences
Focus Developing new mathematical, statistical and computational tools and approaches for modelling biological systems Developing and applying mathematical, statistical, computational and experimental approaches for drug discovery Bioscience and the application of interdisciplinary approaches in the biosciences Synthetic chemistry coupled with an in-depth appreciation of its application to biology and medicine Engineering of Biology: how to design new or redesign existing biological parts, devices and systems for a desired behaviour and functionality Developing new image acquisition, technological or image analysis techniques and apply them to biological or clinical applications
Course Description Four year D.Phil. 12 months based at the DTC doing taught courses and two 10 week rotation projects. No need to identify research area for D.Phil. in advance. Four year D.Phil. 12 months based at the DTC doing taught courses and two 10 week rotation projects. No need to identify research area for D.Phil. in advance. All projects involve an academic partner and an industrial partner. Four year D.Phil. 9 months based at the DTC doing taught courses and two 12 week rotation projects. No need to identify research area for D.Phil. in advance. 12 week Professional Internship in years 2-4 Four year D.Phil. 12 months based at the DTC doing taught courses followed by two 15 week rotation projects. No need to identify research area for D.Phil. in advance. Four year D.Phil. (Oxford) or Ph.D. (Warwick and Bristol). 12 months based at the DTC doing taught courses and two 10-week rotation projects (at least one in Bristol or Warwick for Bristol or Warwick students). No need to identify research area for D.Phil./Ph.D. in advance. Four year D.Phil. (Oxford) or Ph.D. (Nottingham). 12 months based at the DTC doing taught courses and two 10-week rotation projects (at least one in Nottingham for Nottingham-registered students). No need to identify research area for D.Phil./Ph.D. in advance.
Core research areas Systems Biology
  • Detailed pathway modelling
  • Larger scale network modelling
  • Cellular modelling
  • Physiome modelling
Industrial Life Sciences
  • Networks for prediction
  • Target identification and validation
  • Molecular drug design
  • Handling uncertainty in biological models
  • Multi-scale modelling of biological systems
  • Novel therapeutics
  • Data analysis
Fundamental and Applied Bioscience
  • Integrative Animal and Plant Biology
  • Mechanistic Molecular and Cellular Bioscience
  • Bioscience for Food, Industry and Energy
  • Exploiting New Ways of Working
Synthetic Chemistry. Synthesis in 6 Project Fields:
  • New Synthetic Methods
  • 3D Templates for “Lead-Like” Compounds
  • Functional Probes for Epigenetics
  • Next Generation Anti-Infectives
  • Natural Product Chemistry
  • Tools for Neuroscience
Synthetic Biology
  • Synthetic Circuit Design
  • Evolution and Synthetic Biology
  • Synthetic Biology across scales
  • Biomimetic Construction
  • Systems and Control theory for Synthetic Biology
  • Synthetic Communities
Biomedical Imaging
  • Cellular imaging and medical imaging applications
  • Imaging technology
  • Novel image acquisition and reconstruction
  • Post-acquisition image analysis
  • Contrast agents and imaging probes
Closely associated departments at the University of Oxford
  • Biochemistry
  • Chemistry
  • Computing Laboratory
  • Mathematics
  • Plant Sciences
  • Zoology
All biomedical and science departments across the university
  • Biochemistry
  • Plant Sciences
  • Zoology
  • Chemistry
  • Dunn School of Pathology
  • Physiology, Anatomy & Genetics
  • Chemistry
  • Structural Genomics Consortium
All biomedical and science departments across the university
  • Computer Science
  • Engineering Science
  • Chemistry
  • Biochemistry
  • Clinical Neurosciences
  • Oncology
  • Physiology and Anatomy
  • Radcliffe Dept of Medicine
  • And from Nottingham: Sir Peter Mansfield MRI Research Centre, Medicine and Health Sciences, Maths
Links with industry Industrial advisory board. Projects involving industrial partners are supported All short projects and D.Phil. projects include an industrial partner Industrial advisory board. Projects involving industrial partners are supported All short projects and D.Phil. projects include an industrial partner or mentor Industrial advisory board. Projects involving industrial partners are supported Industrial advisory board. Projects involving industrial partners are supported
Core Modules (Oct-Dec)
  • Cells, Signals and Systems or Essential Mathematics and Statistics
  • Introduction to Programming
  • Scientific Computing using Matlab
  • Introduction to Systems and Synthetic Biology
  • Introduction to Experimental Bioscience or Introduction to Organic Chemistry
  • Cells, Signals and Systems or Essential Mathematics and Statistics
  • Introduction to Programming
  • Scientific Computing using Matlab
  • Drug Discovery
  • Introduction to Experimental Bioscience or Introduction to Organic Chemistry
  • Anatomy and Physiology
  • Medicinal Chemistry
  • Essential Mathematics and Statistics or Cells, Signals and Systems
  • Introduction to Programming
  • Scientific Computing Using Matlab
  • Advanced Experimental Techniques
  • Microscopy and Imaging Techniques
  • Introduction to Systems and Synthetic Biology
  • Image Analysis
  • Data Management and Curation
  • Stereocontrol
  • Pharma Disconnections
  • Modern Heterocyclic Chemistry
  • Radicals, Radical Cations and Radical Anions
  • Cells, Signals and Systems
  • Drug Discovery
  • Modern Carbanion Chemistry
  • Metal Catalysis
  • Modern Total Synthesis
  • DFT and Mechanism
  • Case Studies in Physical Organic Chemistry
  • Fluorine
  • Epigenetics
  • Anti-infectives
  • Cells, Signals and Systems or Essential Mathematics and Statistics
  • Introduction to Programming
  • Introduction to Experimental Bioscience
  • Scientific Computing using Matlab
  • Introduction to Systems and Synthetic Biology
  • Introduction to Experimental Bioscience or Image Analysis and Data Management and Curation
  • Cells, Signals and Systems or Essential Mathematics and Statistics
  • Introduction to Light Microscopy
  • Introduction to Medical Imaging Modalities
  • Introduction to Image Analysis
  • Scientific Computing Using Matlab
  • Introduction to Programming
Advanced Modules (Jan-Mar)
  • Statistics
  • Structural Biology
  • Anatomy and Physiology
  • Systems Medicine
  • Mathematical Modelling
  • Structural and Systems Biology Techniques
Further optional courses in years 2-4
  • Statistics
  • Structural Biology
  • Anatomy and Physiology
  • Biomedical Imaging – Design and Imaging
  • High Performance Computing
  • Structural and Systems Biology Techniques
Further optional courses including Entrepreneurship and Project Management in years 2-4
  • DTP students can opt to attend additional courses from those offered within the DTC, via the MPLS Graduate Academic Programme and Medical Science Division Skills Training Programe, or by partner organisations (e.g. Synchrotron and Neutron School (Diamond Light Source and ISIS))
  • DTP students have access to ongoing practice-led training in interdisciplinary skills and inter-DTP training in specialist subjects.
  • Biomedical Imaging – Design and Imaging
  • Structural Biology
  • Advanced NMR
  • X-ray Crystallography
  • Study Design & Clinical Trials
  • Chemistry Entrepeneurship
  • Synthetic Circuit Design
  • Evolution and Synthetic Biology
  • Synthetic Biology Across Scales
  • Systems and Control Theory for Synthetic Biology
  • Biomimetic Construction
  • Synthetic Communities
  • Advanced Methods in Synthetic Biology
  • Wetlab project
  • Ethical, Legal and Societal Aspects of Synthetic Biology
  • Advanced Light Microscopy
  • Advanced Medical Imaging Modalities
  • Advanced Image Analysis
  • High Performance Computing
  • Contrast Agents and Imaging Probes
  • Anatomy and Physiology
  • Study Design, Research Governance and Clinical Trials
  • Mathematical Modelling for Imaging
Research skills training Training in core research skills, including scientific writing, project management and communication. Teaching experience and training. Training in core research skills, including scientific writing, project management, and communication. Teaching experience and training. Additional training in skills relevant to research in industry and at the industrial interface. Training in core research skills, including scientific writing, project management and communication. Teaching experience and training. Entrepreneurship and public engagement training and experience. Training in core research skills, including scientific writing, project management and communication. Teaching experience and training. Training in core research skills, including scientific writing, project management and communication. Teaching experience and training. Public engagement training and experience. Training in core research skills, including scientific writing, project management and communication. Teaching experience and training.