After completing my undergraduate degree in Medical Science at Oxford Brookes University in 2017 and achieving first class honours, I began my DPhil within the Doctoral Training Partnership (DTP) at Oxford University. I look forward to developing both personally and professionally within the DTP over the coming years.
I am particularly interested in cellular communication and the ever-growing field of extracellular vesicles, and their potential for diagnostic and therapeutic exploitation in diverse biological functions. I also enjoy studying neuroscience, and therefore hope to pursue my DPhil within the areas of cellular and vesicle communication and/or aspects of neuroscience.
Royal Veterinary College – During April 2016 I undertook a two week placement with Dr Charlotte Lawson at the Royal Veterinary College, where I shadowed a number of lecturers and students and focused on my own mini-project; a pilot experiment to isolate and measure microvesicles from Zebrafish embryos during inflammation. I assisted students in numerous experimental techniques investigating the role of extracellular vesicles in the immune system.
Oxford Brookes University – As a part of the BBSRC summer research experience I completed a ten week placement supervised by Dr Dave Carter during the summer of 2016. In this time I worked on my own project investigating the role of extracellular vesicle transfer in homeostasis and the stress response within Drosophila Melanogaster. Over this period I learnt to culture and handle Drosophila species.
Alongside my placement, I began to develop a novel and versatile visualization system for vesicle transfer within Drosophila, eliminating some of the current limitations in in vivo exosome research. This entailed several cloning techniques to engineer the system into Drosophila vectors, which allowed me the opportunity to learn cell culture techniques and bioinformatic analysis, as well as develop my lab skills with PCR and gel electrophoresis.
Commencing in January 2018, I will be undertaking a 12 week rotation project in the lab of Dr Dave Carter at Oxford Brookes University, where I will be studying the transfer of Extracellular Vesicles (EVs) between cells under both controlled and stress conditions.
Following in April 2018, I will be using an iPSC-based modelling system to investigate the molecular mechanisms underlying cerebellar development in a 12 week project with Dr Esther Becker of the Department of Physiology, Anatomy and Genetics at Oxford University.
From these two short projects I will ultimately decide where I wish to pursue my final DPhil.
I have attended the annual Extracellular Vesicle forum meeting (UKEV) for the past two consecutive years.