Jan-Sep 2015: Designing new 3D culture assays to determine the role of MAP4 in Breast Cancer cell migration; Dr Anne Straube's lab, Univeristy of Warwick:
I worked as a Graduate Research Assistant. My research involved collecting preliminary data, working with human cell lines. I used fluorescence time-lapse microscopy to examine cell behaviour in a range of conditions. This was used to develop a preliminary new 3D culture system for breast cancer cells, and investigate the role of one gene in cancer cell migration.
Sep-Nov 2014: Investigating BET inhibitor proetins' roles in DNA replication and transcription; Dr Eva Petermann's lab, Univeristy of Birmingham:
This research was funded by the Medical Research Council and the University College of Medical and Dental Science. I spent 6 weeks in the lab of Dr Eva Petermann, doing cancer research. I investigated the role of BET inhibitor proteins on DNA replication and transcription, using DNA fibre and EU transcription assay techniques.
Sep-Dec 2013: Determining the molecular basis of sorbic acid resistance in spoilage fungi; Professor David Archer's lab, University of Nottingham:
I spent 10 weeks part time in the lab of Professor David Archer, investigating the molecular mechanism of sorbic acid resistance in filamentous spoilage fungi.
I designed degenerate primers, based on acid resistance genes in a model species, to look for homologues in related species, and determine if the genetic mechanism in those related species was the same as in the model. I also verified the ability of these strains to metabolise the acid, using GCMS, and verified levels of resistance by MIC (Minimum inhibitory concentration) assays.
Jun-Aug 2012: Investigating Bdellovibrio cell wall proteins; Professor Liz Sockett's lab, Univeristy of Nottingham:
I was awarded an SGM Studentship to do six weeks of research over the summer, 2013. I worked in the lab of Professor Liz Sockett, working on the predatory bacteria Bdellovibrio. Bdellovibrio invades, degrades and then lyses gram negative bacteria, and is being investigated as an alternative to anti-bacterials, since it can evolve to counteract resistance. I co-presented a poster at the 2014 SGM annual conference in Liverpool on the research I carried out.