Teaching

Lecture

Trinity term 2016

Chimeric Antigen Receptor T Cell Therapy

Biochemistry, year 4, University of Oxford
Topics covered:

  • Chimeric antigen receptors in context with other cancer immunotherapies
  • Advantages and disadvantages of different T cell-manipulating strategies
  • Generations of chimeric antigen receptors
  • Receptor design and effects of each domain on T cell activation
  • Advanced strategies and combination approaches

Series of 4 tutorials

Michaelmas term 2016
Hilary term 2016

Fundamental Immunology

Biochemistry, year 3, St. Hugh's College, University of Oxford

Topics covered:

  • Classification of immune cells and organs
  • Acute and chronic inflammation, innate effector cells and molecules
  • Immune response dynamics, links between innate and adaptive immunity
  • Dendritic cells, antigen processing and presentation, implications of MHC diversity
  • Lymphocyte development, receptor rearrangement, selection and activation
  • T cell and B cell subsets, effector functions, antibody classes
  • Exam preparation and mock exam marking

Demonstrator, 2 sessions

Michaelmas term 2016

Cells and Systems

Doctoral Training Centre, University of Oxford
I was the point of contact for an essay-based assessment on inherited immunodeficiencies. I helped the students to identify relevant literature and to structure the problem.

Demonstrator, 4 sessions

Hilary term 2016

Mathematical Medicine and Biology

Doctoral Training Centre, University of Oxford
I was the point of contact for the students' questions as they were developing mathematical models of tumour growth.

Tutorial, 6 sessions

Hilary term 2017
Hilary term 2016
Michaelmas term 2015

Chimeric Antigen Receptor T Cell Therapy

Medicine/Biomedical Sciences, year 3, University of Oxford


Topics covered:

  • Chimeric antigen receptors in context with other cancer immunotherapies
  • Implications of therapeutic approaches using genetically modified living cells
  • Receptor design and effects of each domain on T cell activation
  • Major challenges for the field, toxicities, solid malignancies
  • Advanced strategies and combination approaches and their clinical potential