Samuel Cahill


Personal photo - Samuel Cahill

Samuel Cahill

Doctoral Student in the
Chemistry Research Laboratory, Department of Chemistry

12 Mansfield Road, Oxford OX1 3TA

Current Roles

DPhil student under Prof. Christopher J. Schofield (Department of Chemistry) - Studying the roles of metallo-β-lactamases in antibiotic resistance.
Class Tutor in Biophysical Chemistry (Department of Biochemistry)
Outreach Volunteer at Oxford Museum of the History of Science - Supporting the 'Back from the Dead' exhibition on antibiotics.

Publications

Cahill ST, Cain R, Wang DY, Lohans CT, Wareham DW, Oswin HP, Mohammed J, Spencer J, Fishwick CWG, Mcdonough MA, Schofield CJ, Brem J, Cyclic Boronates Inhibit All Classes of β-Lactamase, Antimicrob. Agents Chemother. 2017, IN PRESS doi:10.1128/AAC.02260-16

Cahill ST, Tarhonskaya H, Ryzdik AM, Flashman E, McDonough MA, Schofield CJ, Brem J, Use of ferrous iron by metallo-β-lactamases, J. Inorg. Biochem. 2016, 163, 185-193 doi:10.1016/j.jinorgbio.2016.07.013

Brem J, Cain R, Cahill S, McDonough MA, Clifton IJ, Jiménez-Castellanos JC, Avison MB, Spencer J, Fishwick CW, Schofield CJ, Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates, Nat. Comm., 2016, 7, 12406
doi:10.1038/ncomms12406

Awards

2016 Poster Prize at BSAC Antibiotic Resistance Mechanisms Workshop for presenting 'Boronates as Broad-Spectrum Inhibitors of β-Lactamases'

Education & Qualifications

2017 -   Associate Fellow of the Higher Education Academy
2013 -   University of Oxford
DPhil with DTP Interdisciplinary Bioscience programme BA (incorp) 2009 - 2013 University of Cambridge
MSc BA (Hons) Natural Sciences - Graduating in Chemistry 2002 - 2009 Colchester Royal Grammar School

DTP Rotation Projects

1st Rotation Project: Structural Studies on the Bacterial Metallo-Beta-Lactamases - Supervisor: Prof. Christopher J. Schofield; Department: Chemistry.

2nd Rotation Project: Mining the Active Plant Proteome - Supervisor: Dr Renier A. L. van der Hoorn; Department: Plant Sciences.

Previous Research & Experience

Masters Dissertation: An RNA Aptamer Mimic of GFP for the Cellular Imaging of Small Molecules and Endogenous RNAs - Supervisor: Prof. Shankar Balasubramanian; Department of Chemistry, University of Cambridge.

Tutoring - particularly in A level chemistry
Laboratory Experience - including four years in chemistry labs and two years in biochemical labs

Interests

Music - including playing the piano and the viola as well as choral singing
Travel - especially in Europe
Cooking