University of Sheffield - 2011-2012 - MSc Mechanistic Biology
University of Sheffield - 2007-2011 - BSc Biochemistry
University of Sheffield - Masters project - January - September 2012 - Creating an agent-based model of the contribution of the structural protein actin to endocytosis in budding yeast using Python. Using a Brownian ratchet mechanism for the elongation stage of endocytosis, the contribution of bundling proteins was assessed using the Monte Carlo method (see blog post).
University of Oxford - summer vacation studentship - June - July 2011 - Modifying several CellML models of cardiac purkinje cells, adding a stretch activated current parameter. Finding and reviewing scientific literature, familiarising myself with the XML-based language and Cellular Open Resource, and collecting data, including writing a peak detection macro in OpenOffice Calc Basic. I also had the opportunity to observe voltage-sensitive dye experiments on the whole heart, single purkinje cells and the intact ventricular wall, and to attend the Physiology 2011 conference (see blog post).
University of Sheffield - summer vacation studentship - June - July 2010 - Investigating the effects of zinc on the formation of Stefin B amyloid fibrils. This work included: plasmid preparation/harvesting; creation of competent E. coli cells; transformation; cell growth and harvesting; protein purification including ion exchange chromatography, size exclusion chromatography and HPLC; SDS-PAGE; UV, visible and fluorescence spectroscopy; circular dichroism; electron microscopy; data handling using Microsoft Excel and Visual Basic Scripting; and critical analysis of scientific literature. This project culminated in a written report, a podcast and two presentations to technical and non-technical audiences (see blog post).